Arizona Wines 101

Alcantara Vineyards – Cottonwood

Co-founder Barbara Predmore's Under the Tuscan Sun fantasies brought her to the confluence of Oak Creek and the Verde River, where she and her husband Bob planted more than 13,000 vines encompassing a dozen grape varietals.

"The rocky limestone soil and sunny climate in the Verde are very similar to the winemaking regions of France and Italy," Predmore notes on the winery's website, "and after two years of experimentation the results are everything we hoped for and then some."

Alcantara's on-site tasting room is a pit stop for local kayakers. Pop in wet or dry for a sampler of five wines.

Caduceus Cellars – Jerome

Tool frontman Maynard James Keenan, who moved to Arizona in 1995, said the "mystical" terrain around Sedona inspired him to plant a vineyard. "Most of those I shared this vision with just sort of nodded and secretly hoped I would stay on my meds," he quips on the Caduceus Cellars website.

The winery and Keenan's associated Merkin Vineyards focus on Spanish and Italian varietals grown at high elevations on the slopes of Jerome's southeast-facing hills, producing 4,500 cases annually. Open daily—yes, even on Christmas—its Main Street tasting room offers glasses of cheekily named vintages such as Merkin's Chupacabra Rosa and Shinola.

Page Springs Cellars – Cornville

Located less than 20 minutes south of downtown Sedona, Page Springs Cellars offers a taste of the luxe tourist town with a more wallet-friendly, rural feel. The area's climate is similar to that of the Mediterranean and the soil is alkaline, lending itself naturally to Rhône-style varietals including Traminette and Syrah.

On the weekends, adults can tour part of the five-and-a-half-acre estate vineyard planted in 2003 by winemaker Eric Glomski. Relaxation options for guests include yoga and a chair massage among the vines.

Keeling-Schaeffer Vineyards

Technically, the roots of Keeling-Schaefer are in California. After grafting, established vines are then shipped to Arizona for planting a year later. More than 20 of Keeling-Schaefer's wines have been rated by Wine Spectator, with three scoring an 89 (one of the highest ratings for an Arizona wine).

While the home field is in Pearce, 41 miles from Willcox, tastings are held in the historic 1917 Willcox Bank and Trust building. Founder Rod Keeling and his wife Jan actually lived in that tasting room while their vineyard villa was under construction.

Callaghan Vineyards

When the POTUS drinks your wine, you know you're fermenting with the big boys. Callaghan vino has made guest appearances at White House events including a Clinton dinner and former Justice Sandra Day O'Connor's retirement.

"Our winemaking approach is decidedly simplistic—no gizmos, lots of barrels (new to four years old), aging on the lees, and little racking," founder Kent Callaghan says. On-site tastings are equally no-fuss yet elegant; stop in on the weekend for a tasting (crystal glass included), and you'll likely meet Callaghan in the flesh.

Dos Cabezas Wineworks

Two heads are better than one—or in this case, two vineyards are better than one. The dry, fruity reds and mild whites of Dos Cabezas come from dual growing parcels: Pronghorn Vineyard in Elgin and Cimarron Vineyard in the Kansas Settlement near Willcox.

The Sonoita tasting room is rustic and homey, with past pours ranging from a deep red to a funky, sparkling pink wine served in a can. The latter's rosy label design is taken from a painting by Leonard Bianco, whose son Chris owns Phoenix's award-winning Pizzeria Bianco.